Position Description:
We're looking for those individuals-the creative thinkers and innovation seekers-who are content with nothing short of changing the world. Discover the endless opportunities within the Medical College of Wisconsin (MCW) and be inspired by the work we can do together to improve health, and make a positive, daily impact in our communities. Purpose: A Postdoctoral Fellow Position is immediately available in the laboratory of Dr. Anthony E. Zamora in the Division of Hematology and Oncology, Department of Medicine at the Medical College of Wisconsin. The Zamora lab's research focuses on identifying ways to modulate the immune system to more effectively target and eliminate cancerous cells. Along these lines, the lab utilizes cellular-based engineering approaches that aim to increase the specificity of immune cells for their targets and at the same time decrease the likelihood of off-target toxicities. Current research in the Zamora lab focuses on: (1) discovering tumor antigens that serve as immunogenic targets, (2) identifying the mechanisms involved in the immune system's ability to generate antitumor specificities, (3) characterizing the phenotypic, functional, and receptor repertoires of neoantigen-specific T cells, and (4) exploring ways to translate these findings to expand on the current therapeutic options used to treat cancer. A major area of focus for this postdoctoral position will be to work on preclinical and translational studies focused on assessing the efficacy of novel CAR T cell therapies. Work for this project will consist of determining whether non-viral genome targeting approaches utilizing endogenous gene expression pathways show improved persistence, functionality, and safety when compared to traditional non-targeted viral gene delivery systems. Experience with flow cytometry, PCR, RNA-seq, molecular cloning, cell culture, and other immunological techniques is required. Previous experience with sequencing, single-cell analysis, computational/bioinformatic analysis is highly desired. This position is NOT RESTRICTED to permanent U.S. residents or citizens. Characteristics of a postdoctoral appointment: It is expected that postdocs at MCW, with the assistance of their supervisor, will: Primary Functions
Position Summary
Preferred Schedule:
Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs.
Position Requirements:
Knowledge - Skills - Abilities Organizational Structure Building: MACC Fund Research Building, Suite 6072 Department: Medicine Division: Hematology and Oncology Reports to (Title): Principal Investigator - Dr. Anthony E. Zamora Collaborates with (Titles): Rotating Students, Graduate Student Researchers, Research Staff Specifications Minimum Required Education: PhD in Immunology, Molecular Biology, or a related field. Minimum Required Experience: No experience required Preferred Education: PhD in Immunology, Molecular Biology, Cancer Biology, Computational Biology/Bioinformatics, Systems Biology Preferred Experience: Experience in immunology, molecular and cellular biology techniques. Immunology, molecular and cellular biology, cancer biology, and/or cancer immunotherapy research. Computational Biology/Bioinformatics experience/research desired. Why MCW? For a full list of positions see: www.mcw.edu/careers For a brief overview of our benefits see: https://www.mcw.edu/departments/human-resources/benefits Eastern Wisconsin is a vibrant, diverse metropolitan area. MCW is intent on attracting, developing, and retaining a diverse workforce and faculty body that reflects the community we serve. We value diversity of backgrounds, experience, thought, and perspectives to advance excellence in science and medicine. MCW is a welcoming campus community with a strong culture of collaboration, partnership, and engagement with our surrounding community. For more information, please visit our institutional website at https://www.mcw.edu/departments/office-of-diversity-and-inclusion.
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MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination
The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.
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